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A suggested positive control is SK-N-SH cell lysate.
PA5-20363 can be used with blocking peptide PEP-0483.
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain-specific serine protease 3; BSSP-3; Leydin; Motopsin; Neurotrypsin; peptidase, serine, 12 (neurotrypsin, motopsin); protease, serine, 12 (neurotrypsin, motopsin); protease, serine, 12 neurotrypsin (motopsin); Serine protease 12
基因别名: BSSP-3; BSSP3; motopsin; MRT1; Nt; PRSS12
UniProt ID: (Human) P56730, (Rat) G3V801, (Mouse) O08762
Entrez Gene ID: (Human) 8492, (Rat) 85266, (Mouse) 19142