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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: WVSVTDFGAP CLRWAEVPPF LERSPPASWA QLRGQRHNFC RSPDGAGRPW CFYGDARGKV DWGYCDCRHG SVRLRGGK
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 72%.
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: brain-specific serine protease 3; leydin; protease, serine 12; protease, serine, 12 (neurotrypsin, motopsin)
基因别名: BSSP-3; BSSP3; MRT1
UniProt ID: (Human) P56730
Entrez Gene ID: (Human) 8492