Invitrogen

Nidogen G2 Domain Monoclonal Antibody (JF4)

Name: Nidogen G2 Domain Monoclonal Antibody (JF4)
Brand: Invitrogen
SKU: MA5-17017

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MA5-17017

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

酶联免疫吸附实验 (ELISA)

Assay-dependent

抑制试剂 (IA)

Assay-dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Rat / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

JF4

抗原

Recombinant fragment corresponding to the G2 region of mouse nidogen produced in Fisher rat plus YB2/0 cells

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

2M tris, 0.5M acetic acid

内含物

0.1% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2538489

产品详细信息

MA5-17017 recognizes native and denatured mouse and human nidogen, and blocks binding of nidogen to laminin.

MA5-17017 has been successfully used in ELISA and Western blot applications.

The MA5-17017 immunogen is a recombinant fragment corresponding to the G2 region of mouse nidogen produced in Fisher rat plus YB2/0 cells.

靶标信息

Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Although the precise composition and structure of basal laminae varies from tissue to tissue, as well as within the same tissue at different developmental stages, most mature basal laminae contain type IV collagen, laminins, heparan sulphate proteoglycans and entactin (or nidogen). Entactin is a sulfated glycoprotein that is widely distributed in basement membranes. It is tightly associated with laminin and also binds to collagen IV. Entactin probably has a role in cell-extracellular matrix interactions.

仅用于科研。不用于诊断过程。未经明确授权不得转售。