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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total OAS2.
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates. These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: (2-5')oligo(A) synthase 2; 2',5'-oligoadenylate synthetase-like 11; 2'-5' oligoadenylate synthetase-like 11; 2'-5'-oligoadenylate synthase 2; 2,5-oligoadenylate synthetase-like 11; 2-5A synthase 2; A synthetase 2; MGC78578; p69 OAS / p71 OAS; p69OAS / p71OAS
基因别名: OAS2; Oasl11
UniProt ID: (Mouse) E9Q9A9
Entrez Gene ID: (Mouse) 246728