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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • OPHN1 Antibodies

          Abnova

          OPHN1 Monoclonal Antibody (2B9)

          查看其他5个OPHN1抗体

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          说明书
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          Cite OPHN1 Monoclonal Antibody (2B9)

          • 抗体检测数据 (1)
          OPHN1 Antibody in ELISA (ELISA)
          Group 53 Created with Sketch.
          OPHN1 Antibody in ELISA (ELISA)
          Group 53 Created with Sketch.

          图: 1 / 1

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          OPHN1 Antibody (H00004983-M03) in ELISA

          Detection limit for recombinant GST tagged OPHN1 is approximately 0.3 ng/mL as a capture antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
          已发表图片由___提供 benchsci-logo
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          查看产品

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          OPHN1 Antibody in ELISA (ELISA)
          OPHN1 Monoclonal Antibody (2B9)

          产品信息

          H00004983-M03

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1-5 µg/mL
          -

          酶联免疫吸附实验 (ELISA)

          10 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG2a, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          2B9

          抗原

          OPHN1 (NP_002538, 641 a.a. approximately 734 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.5-1 mg/mL

          纯化类型

          Protein A

          保存液

          PBS, pH 7.4

          内含物

          no preservative

          保存条件

          -20°C, Avoid Freeze/Thaw Cycles

          运输条件

          Ambient (domestic); Wet ice (international)

          产品详细信息

          Product may be used with Sandwich ELISA (Recombinant protein).

          Immunogen sequence: QRSGETDPGR KSPSRPILDG KLEPCPEVDV GKLVSRLQDG GTKITPKATN GPMPGSGPTK TPSFHIKRPA PRPLAHHKEG DADSFSKVRP PGEK

          靶标信息

          Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: mental retardation, X-linked 60; Oligophrenin-1; oligophrenin-1, Rho-GTPase activating protein

          查看更多 收起

          基因别名: ARHGAP41; MRX60; OPHN1; OPN1

          查看更多 收起

          UniProt ID: (Human) O60890

          查看更多 收起

          Entrez Gene ID: (Human) 4983

          查看更多 收起

          功能
          actin binding GTPase activator activity phospholipid binding ionotropic glutamate receptor binding GTPase-activating protein
          参与通路
          substrate-dependent cell migration, cell extension signal transduction nervous system development axon guidance actin cytoskeleton organization regulation of endocytosis positive regulation of GTPase activity synaptic vesicle endocytosis regulation of small GTPase mediated signal transduction regulation of synaptic transmission, glutamatergic negative regulation of proteasomal protein catabolic process
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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