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Invitrogen
OPRD1 Recombinant Rabbit Monoclonal Antibody (6F2)
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OPRD1 Antibody (MA572566) in WB
Western blot analysis of OPRD1 in Rat brain and Human umbilical cord lysates (25 µg/lane). Samples were incubated with OPRD1 Recombinant Monoclonal (Product # MA572566) at 1:2,000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.
产品信息
MA572566
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6F2
抗原
KLH conjugated synthetic peptide derived from human DOR 1.
偶联物
形式
Liquid
浓度
0.4 mg/mL
规格
40 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
OPRD1 is an Opioid Receptor that is involved in the control of anxiety, depression, and pain. It is a promising target in the therapy of mood-altering disorders and drug addiction. Delta and kappa opioid receptors function synergistically by forming heterodimers. OPRD1 expression has been reported primarily in the brain. High OPRD1 expression has been documented in the cortex, caudate, hippocampus, nucleus accumbens, and putamen; low OPRD1 expression has been identified in the cerebellum, hypothalamus, substantia nigra, and thalamus. OPRD1 expression is reduced in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D-OR-1; delta 1 opioid receptor; delta opioid receptor 1; Delta-type opioid receptor; DOR-1; K56; MSL-2; Opioid receptor; Opioid receptor A
基因别名: DOP; DOR; DOR-1; DOR1; mDOR; Nbor; OPRD; OPRD1; Ror-a
UniProt ID: (Human) P41143, (Mouse) P32300, (Rat) P33533
Entrez Gene ID: (Human) 4985, (Mouse) 18386, (Rat) 24613
immune response
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
adult locomotory behavior
negative regulation of gene expression
negative regulation of protein complex assembly
response to nicotine
opioid receptor signaling pathway
eating behavior
response to ethanol
regulation of mitochondrial membrane potential
regulation of calcium ion transport
cellular response to growth factor stimulus
cellular response to hypoxia
cellular response to toxic substance
protein import into nucleus, translocation
adenylate cyclase-activating dopamine receptor signaling pathway
chemical synaptic transmission
negative regulation of protein oligomerization
positive regulation of peptidyl-serine phosphorylation
regulation of sensory perception of pain
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