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Invitrogen
OSCAR Polyclonal Antibody
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产品信息
PA5-47238
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human OSCAR isoform 2 Asp19-Asn229 (Asn158Ser)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Approximately 25% cross-reactivity with recombinant mouse OSCAR is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC33613; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIgR-3; poly-Ig receptor 3; Polymeric immunoglobulin receptor 3
基因别名: OSCAR; PIgR-3; PIGR3
UniProt ID: (Human) Q8IYS5
Entrez Gene ID: (Human) 126014
