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Reconstitute at 0.5 mg/mL in sterile PBS.
Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC33613; Ocl178; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; osteoclast-associated receptor OSCAR
基因别名: mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3; Oscar
UniProt ID: (Mouse) Q8VBT3
Entrez Gene ID: (Mouse) 232790