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Immunogen sequence: FEGSANKIGV GVVRDGKVLA NPRRTYVTPP GTGFLPGDTA RHHRAVILDL LQEALTESGL TSQDIDCIAY TKGP
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hOSGEP; N6-L-threonylcarbamoyladenine synthase; O-sialoglycoprotein endopeptidase; OSGEP; probable O-sialoglycoprotein endopeptidase; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP; tRNA N6-adenosine threonylcarbamoyltransferase; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP
基因别名: GCPL1; KAE1; OSGEP; OSGEP1; PRSMG1
UniProt ID: (Human) Q9NPF4
Entrez Gene ID: (Human) 55644
分子生物学功能: RNA processing factor