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Invitrogen
OXCT1 Recombinant Mouse Monoclonal Antibody (KBL001_10D10)
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OXCT1 Antibody (MA564490) in IP
Immunoprecipitation of OXCT1 in HeLa lysate (200 µg total protein). Samples were incubated with OXCT1 recombinant monoclonal (Product # MA564490) using a dilution of 2.5 µg After absorption with Protein G beads, the mixture was run on 6-18% SDS-PAGE and blotted onto nitrocellulose membrane. OXCT1 at 0.5 µg/mL was used as the primary antibody and peroxidase conjugated rabbit anti-mouse IgG (Light chain specific) was used as the secondary antibody. The isotype control antibody was KT82. Lane 1: HeLa lysate; Lane 2: OXCT1 immunoprecipitated f... View More
产品信息
MA564490
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
KBL001_10D10
抗原
Recombinant human OXCT1 (aa 40-520).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TKFYTDPVEA VKDIPDGATV LVGGFGLCGI PENLIDALLK TGVKGLTAVS NNAGVDNFGL GLLLRSKQIK RMVSSYVGEN AEFERQYLSG ELEVELTPQG TLAERIRAGG AGVPAFYTPT GYGTLVQEGG SPIKYNKDGS VAIASKPREV REFNGQHFIL EEAITGDFAL VKAWKADRAG NVIFRKSARN FNLPMCKAAE TTVVEVEEIV DIGAFAPEDI HIPQIYVHRL IKGEKYEKRI ERLSIRKEGD GEAKSAKPGD DVRERIIKRA ALEFEDGMYA NLGIGIPLLA SNFISPNITV HLQSENGVLG LGPYPRQHEA DADLINAGKE TVTILPGASF FSSDESFAMI RGGHVDLTML GAMQVSKYGD LANWMIPGKM VKGMGGAMDL VSSAKTKVVV TMEHSAKGNA HKIMEKCTLP LTGKQCVNRI ITEKAVFDVD KKKGLTLIEL WEGLTVDDVQ KSTGCDFAVS PKLMPMQQIA N
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%, Pig - 92%, Cynomolgus monkey - 99%.
靶标信息
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; 3-oxoacid-CoA transferase 1; SCOT; SCOT-s; somatic-type succinyl CoA:3-oxoacid CoA-transferase; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; succinyl CoA:3-oxoacid CoA transferase; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-ketoacid-CoA transferase; succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial; Succinyl-CoA:3-oxoacid CoA transferase
基因别名: OXCT; OXCT1; SCOT
UniProt ID: (Human) P55809
Entrez Gene ID: (Human) 5019
brain development
heart development
response to nutrient
response to hormone
response to activity
positive regulation of insulin secretion involved in cellular response to glucose stimulus
ketone catabolic process
response to drug
response to starvation
response to ethanol
cellular ketone body metabolic process
ketone body catabolic process
adipose tissue development
