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Invitrogen
Ocrelizumab Humanized Recombinant Human Monoclonal Antibody
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Ocrelizumab Humanized Antibody (MA5-59573) in Flow
Flow cytometry analysis of Ocrelizumab Recombinant monoclonal antibody (Product # MA5-59573). Human CD20 CHO-K1 cells were stained with (ocrelizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.48 µg/mL.
产品信息
MA5-59573
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Protein A
保存液
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
靶标信息
Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with relapsing or primary progressive forms of multiple sclerosis. It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets the B lymphocytes that express the CD20 antigen. As a humanized molecule, ocrelizumab is expected to be less immunogenic with repeated infusions which improves the benefit-to-risk profile for patients with relapsing or progressive forms of MS.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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