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Fabgennix
Orexin A Polyclonal Antibody, Biotin
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产品信息
ORXN-BIOTIN
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 1-50 on ORXN protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hcrt; Hypocretin; Hypocretin (orexin) neuropeptide; Hypocretin neuropeptide precursor; orexin; orexin A; orexin B; Orexin precursor; Prepro-orexin; Preprohypocretin
基因别名: Hcrt; orexin-A; Ox; PPOX
UniProt ID: (Mouse) O55241, (Rat) O55232
Entrez Gene ID: (Mouse) 15171, (Rat) 25723
temperature homeostasis
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
feeding behavior
negative regulation of DNA replication
eating behavior
negative regulation of potassium ion transport
regulation of neurotransmitter secretion
positive regulation of calcium ion transport
negative regulation of transmission of nerve impulse
positive regulation of transmission of nerve impulse
excitatory postsynaptic potential
behavioral fear response
release of sequestered calcium ion into cytosol
