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Invitrogen
Orexin A Polyclonal Antibody
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产品信息
PA1-9583
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 1-13 of human Orexin A.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-9583 detects Orexin A in human, mouse, and rat samples.
PA1-9583 has been successfully used in ELISA procedures.
PA1-9583 immunogen is a synthetic peptide corresponding to amino acids 1-13 (AQPLPDCCRQKTC) of human Orexin A.
靶标信息
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hcrt; Hypocretin; Hypocretin (orexin) neuropeptide; Hypocretin neuropeptide precursor; orexin; orexin A; orexin B; Orexin precursor; Prepro-orexin; Preprohypocretin
基因别名: HCRT; NRCLP1; orexin-A; OX; PPORX; PPOX
UniProt ID: (Human) O43612, (Mouse) O55241, (Rat) O55232
Entrez Gene ID: (Human) 3060, (Mouse) 15171, (Rat) 25723
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
neuropeptide signaling pathway
chemical synaptic transmission
negative regulation of DNA replication
eating behavior
negative regulation of potassium ion transport
regulation of neurotransmitter secretion
positive regulation of calcium ion transport
negative regulation of transmission of nerve impulse
positive regulation of transmission of nerve impulse
excitatory postsynaptic potential
temperature homeostasis
feeding behavior
behavioral fear response
release of sequestered calcium ion into cytosol
