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Invitrogen
Otelixizumab Humanized Recombinant Human Monoclonal Antibody
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Otelixizumab Humanized Antibody (MA5-41836) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human CD3E protein expressed in CHO cells using a Otelixizumab biosimilar monoclonal antibody (Product # MA5-41836). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-41836
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, lambda
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human CD3E
偶联物
形式
Liquid
浓度
3.95 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Otelixizumab is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. Otelixizumab is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity. Tolerx is developing otelixizumab to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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