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Invitrogen
Oxytocin Receptor Polyclonal Antibody
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产品信息
PA5-34065
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Oxytocin Receptor.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey, Mouse, Elephant, Panda, Pig (95%).
靶标信息
The oxytocin receptor (OXTR) belongs to the G-protein coupled receptor family. Its activity is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. The receptor is made up of 389 amino acids and has a molecular weight of ~43,000 kDa. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium or the uterus at the end of pregnancy. Additionally, oxytocin receptors are present in the central nervous system, mediating a variety of behaviors, including maternal behavior, bonding, social memory and recognition, sexual and aggressive behaviors, and stress and anxiety.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: OT-R; Oxt-r; Oxytocin receptor
基因别名: OT-R; OXTR
UniProt ID: (Human) P30559
Entrez Gene ID: (Human) 5021
suckling behavior
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
muscle contraction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
heart development
female pregnancy
lactation
memory
positive regulation of norepinephrine secretion
telencephalon development
sleep
positive regulation of synaptic transmission, GABAergic
response to estradiol
response to progesterone
cellular response to hormone stimulus
response to anoxia
response to cytokine
social behavior
response to cocaine
response to drug
maternal behavior
sperm ejaculation
eating behavior
response to peptide hormone
estrous cycle
positive regulation of blood pressure
positive regulation of vasoconstriction
digestive tract development
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
maternal process involved in parturition
positive regulation of penile erection
negative regulation of gastric acid secretion
ERK1 and ERK2 cascade
positive regulation of uterine smooth muscle contraction
response to peptide
