Invitrogen

P-Cadherin Monoclonal Antibody (CSTEM29), APC, eBioscience™

Name: P-Cadherin Monoclonal Antibody (CSTEM29), APC, eBioscience\u2122
Brand: Invitrogen
SKU: 17-2237-42

查看其他24个P-cadherin抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

P-Cadherin Antibody in Flow Cytometry (Flow)

图: 1 / 1

P-Cadherin Antibody (17-2237-42) in Flow

Staining of a mixture of human iPSC and the C2C12 murine cell line with Anti-Human TRA-1-60 PE (Product # 12-8863-82) and Mouse IgG2a K Isotype Control APC (Product # 17-4724-81) (left) or Anti-Human P-Cadherin APC (right).

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产品信息

17-2237-42

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

5 µL (0.25 µg)/test

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

CSTEM29

偶联物

APC APC APC

激发/发射光谱

651/660 nm 查看光谱

形式

Liquid

浓度

5 µL/Test

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2, with BSA

内含物

0.09% sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_2688227

产品详细信息

This monoclonal antibody CSTEM29 reacts with human P-Cadherin, also known as Cadherin-3.

Applications Reported: This CSTEM29 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This CSTEM29 antibody has been pre-diluted and tested by flow cytometric analysis of normal human induced pluripotent stem cells. This may be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser.

Filtration: 0.2 µm post-manufacturing filtered.

靶标信息

P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CADH3; cadherin 3, type 1, P-cadherin (placental); Cadherin-3; calcium-dependent adhesion protein, placental; P-cadherin; Placental cadherin; Placental-cadherin

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基因别名: CDH3; CDHP; HJMD; PCAD

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UniProt ID: (Human) P22223

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Entrez Gene ID: (Human) 1001

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功能

molecular_function calcium ion binding cadherin

参与通路