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Alomone Labs, LTD
P2X5 Receptor (extracellular) Polyclonal Antibody
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P2X5 Receptor (extracellular) Antibody (APR-027-200UL) in WB
Western blot analysis of rat heart (lanes 1 and 3) and mouse heart (lanes 2 and 4): - 1,2. Anti-P2X5 Receptor (extracellular) Antibody (#APR-027), (1:400).3,4. Anti-P2X5 Receptor (extracellular) Antibody , preincubated with P2X5 Receptor (extracellular) Blocking Peptide (#BLP-PR027).
产品信息
APR-027-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)HRSHTRLAEMKYE, corresponding to amino acid residues 299-311 of rat P2X5 receptor, Extracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
规格
170 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The P2X5 gene encodes a protein that is a member of the purinergic receptor family, P2X receptors. These receptors are ligand-gated ion channels activated by extracellular ATP. The P2X5 protein is primarily involved in the regulation of skeletal muscle, immune response, and sensory neuron functions. Structurally, P2X5 features two transmembrane domains, a large extracellular loop, and intracellular N- and C-termini. P2X5 is known to form both homomeric and heteromeric channels, contributing to its functional diversity in various tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP receptor; Membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250|UniProtKB:Q8R3L0}; MGC47755; mmgt2; mmgt2 {ECO:0000250|UniProtKB:Q8R3L0}; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X5-2
基因别名: AI852046; Mmgt2; P2rx5; P2X5; RGD1311260
UniProt ID: (Rat) Q6P719, (Mouse) Q8R3L0, (Mouse) Q91VE2, (Rat) P51578
Entrez Gene ID: (Rat) 303211, (Mouse) 216829, (Mouse) 94045, (Rat) 113995
magnesium ion transmembrane transporter activity
copper ion transmembrane transporter activity
manganese ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
nickel cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
purinergic nucleotide receptor activity
extracellular ATP-gated cation channel activity
ATP binding
GTP binding
drug binding
zinc ion binding
ligand-gated ion channel
magnesium ion transport
transport
cation transport
cobalt ion transport
copper ion transport
manganese ion transport
nickel cation transport
copper ion transmembrane transport
nickel cation transmembrane transport
manganese ion transmembrane transport
cell surface receptor signaling pathway
neuronal action potential
purinergic nucleotide receptor signaling pathway
regulation of skeletal muscle tissue regeneration
protein homooligomerization
cation transmembrane transport
mitophagy in response to mitochondrial depolarization
skeletal muscle tissue growth
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