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Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and shares 86% identity with human sequence.
Specificity of this antibody: P2RX6.
P2rx6 encodes receptors that are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each P2rx6 receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains. The protein encoded by the P2rx6 gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. The P2rx6 gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants of P2rx6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP receptor; P2X purinoceptor 6; P2X6; P2X6 receptor; P2XM; Purinergic receptor; Purinergic receptor P2X-like 1; purinergic receptor P2X-like 1 orphan receptor; purinergic receptor P2X-like 1, orphan receptor; purinergic receptor P2X6
基因别名: P2rx6; P2rxl1; P2x6; P2xm; Rnap2x6
UniProt ID: (Rat) P51579, (Mouse) O54803
Entrez Gene ID: (Rat) 25041, (Mouse) 18440
分子生物学功能: ligand-gated ion channel