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Invitrogen
P2Y1 Polyclonal Antibody
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产品信息
PA5-34071
产品规格
种属反应
Bat,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 15 amino acid peptide from 2nd extracellular domain of human P2RY1 / P2Y1.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Bat (100%).
靶标信息
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP receptor; ATP receptor; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; p2y-1-r; P2Y1; p2y1r; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled, 1; Purinoceptor p2y1; Purinoceptor p2yr1; suppressing androgen receptor in renal cell carcinoma; unnamed protein product
基因别名: P2RY1; P2Y1; SARCC
UniProt ID: (Human) P47900
Entrez Gene ID: (Human) 5028
nucleotide binding
ADP receptor activity
G-protein coupled receptor activity
protein binding
ATP binding
receptor regulator activity
A1 adenosine receptor binding
signaling receptor activity
ADP binding
G-protein coupled purinergic nucleotide receptor activity
ATP-activated adenosine receptor activity
protein heterodimerization activity
scaffold protein binding
adenosine receptor signaling pathway
ion transport
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood coagulation
hemostasis
glial cell migration
regulation of cell shape
response to mechanical stimulus
negative regulation of norepinephrine secretion
signal transduction involved in regulation of gene expression
platelet activation
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
eating behavior
positive regulation of ion transport
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
establishment of localization in cell
positive regulation of penile erection
positive regulation of ERK1 and ERK2 cascade
response to growth factor
cellular response to ATP
cellular response to purine-containing compound
protein localization to plasma membrane
relaxation of muscle
regulation of blood vessel diameter
regulation of presynaptic cytosolic calcium ion concentration
regulation of synaptic vesicle exocytosis
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