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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody is predicted to react with mouse, rat, canine, bovine, and chicken based on sequence homology.
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein kinase C and casein kinase substrate in neurons 2 protein; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; SdpIIsyndapin II; Synaptic dynamin-associated protein II; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; x-PACSIN2
基因别名: AI197433; PACSIN2; SdpII; XELAEV_18019736mg
UniProt ID: (Rat) Q9QY17, (Mouse) Q9WVE8, (Xenopus) Q9DDA9
Entrez Gene ID: (Rat) 124461, (Mouse) 23970, (Xenopus) 398138