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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: PAD4-transfected 293T.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PAD type IV; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4
基因别名: Pad4; Padi4; Pdi4
UniProt ID: (Mouse) Q9Z183
Entrez Gene ID: (Mouse) 18602