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Invitrogen
PAF1 Polyclonal Antibody
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产品信息
PA5-30751
产品规格
种属反应
Human,
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PAF1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.37 mg/mL
规格
37 µg
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (92%), Xenopus laevis (93%), Chimpanzee (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hPAF1; Paf1, RNA polymerase II associated factor, homolog; paf1, RNA polymerase II associated factor, homolog, like; Pancreatic differentiation protein 2; PD2-like protein; RNA polymerase II-associated factor 1 homolog; unnamed protein product
基因别名: 5730511K23Rik; AA675045; F23149_1; im:6906070; PAF1; paf1l; PD2; wu:fb80a09
UniProt ID: (Human) Q8N7H5, (Mouse) Q8K2T8, (Zebrafish) Q4U0S5
Entrez Gene ID: (Human) 54623, (Mouse) 54624, (Zebrafish) 553020
negative regulation of transcription from RNA polymerase II promoter
endodermal cell fate commitment
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA polyadenylation
histone monoubiquitination
Wnt signaling pathway
nucleosome positioning
stem cell population maintenance
positive regulation of histone methylation
positive regulation of mRNA 3'-end processing
positive regulation of transcription elongation from RNA polymerase II promoter
histone H2B ubiquitination
protein localization to nucleus
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
transcription elongation from RNA polymerase II promoter
mRNA 3'-end processing
positive regulation of cell cycle G1/S phase transition
heart development
histone modification
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