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PAFAH1B1 Monoclonal Antibody (2C12)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00005048-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2C12
抗原
PAFAH1B1 (NP_000421, 1 a.a. approximately 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MVLSQRQRDE LNRAIADYLR SNGYEEAYSV FKKEAELDVN EELDKKYAGL LEKKWTSVIR LQKKVMELES KLNEAKEEFT SGGPLGQKRD PKEWIPRPPE KYALSGHRSP
靶标信息
VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: lissencephaly 1 protein; MGC25297; PHFAH1B1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); RP23-194P5.2; unnamed protein product
基因别名: LIS1; LIS2; MDCR; MDS; NudF; PAFAH
UniProt ID: (Human) P43034
Entrez Gene ID: (Human) 5048
establishment of mitotic spindle orientation
microtubule cytoskeleton organization
acrosome assembly
neuron migration
microtubule-based process
nuclear migration
chemical synaptic transmission
nervous system development
neuroblast proliferation
learning or memory
retrograde axonal transport
adult locomotory behavior
negative regulation of neuron projection development
stem cell division
transmission of nerve impulse
corpus callosum morphogenesis
hippocampus development
layer formation in cerebral cortex
cerebral cortex neuron differentiation
cerebral cortex development
actin cytoskeleton organization
forebrain development
microtubule organizing center organization
reelin-mediated signaling pathway
positive regulation of embryonic development
establishment of planar polarity of embryonic epithelium
cortical microtubule organization
positive regulation of axon extension
positive regulation of mitotic cell cycle
platelet activating factor metabolic process
vesicle transport along microtubule
brain morphogenesis
modulation of synaptic transmission
neuromuscular process controlling balance
microtubule sliding
positive regulation of cellular component organization
establishment of organelle localization
establishment of centrosome localization
auditory receptor cell development
positive regulation of dendritic spine morphogenesis
platelet activating factor catabolic process
regulation of microtubule cytoskeleton organization
cochlea development
microtubule cytoskeleton organization involved in establishment of planar polarity
regulation of postsynapse organization
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