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Invitrogen
PARD3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-49856
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from internal of human PARD3.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total PARD3 protein.
Target Information
This gene encodes a member of the kinesin 4 or subfamily of kinesin related proteins. This subfamily is also referred to as the chromokinesins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASBP; ASIP; Atypical PKC isotype-specific-interacting protein; atypical PKC-specific binding protein; Atypical PKC-specific-binding protein; CTCL tumor antigen se2-5; Ephrin-interacting protein; FLJ21015; PAR-3; par-3 (partitioning defective 3) homolog; PAR3-alpha; PARD-3; Partitioning defective 3 homolog; partitioning-defective 3 homolog; PHIP; RP11-406D17.1; three-PDZ containing protein similar to C. elegans PAR3 (partitioning defect)
Gene Aliases: AA960621; AI256638; Asip; D8Ertd580e; Par-3; PAR3; PAR3A; Pard-3; PARD3; Pard3a; Phip
UniProt ID: (Mouse) Q99NH2, (Rat) Q9Z340
Entrez Gene ID: (Mouse) 93742, (Rat) 81918
microtubule cytoskeleton organization
apical constriction
protein targeting to membrane
cell cycle
establishment or maintenance of cell polarity
negative regulation of peptidyl-threonine phosphorylation
single organismal cell-cell adhesion
myelination in peripheral nervous system
cell differentiation
positive regulation of myelination
regulation of actin filament-based process
wound healing, spreading of cells
cell division
centrosome localization
regulation of cellular localization
bicellular tight junction assembly
establishment of epithelial cell polarity
establishment or maintenance of epithelial cell apical/basal polarity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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