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Antibodies Inc
PARIS/ZNF746 Monoclonal Antibody (N196/16), FL594
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产品信息
75-195-FL594
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N196/16
抗原
Fusion protein amino acids 1-322 (N-terminus) of human ZNF746 (accession number Q6NUN9) produced recombinantly in E. Coli.
偶联物
激发/发射光谱
594/615 nm
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
靶标信息
ZNF746 is a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and represses transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PARIS; parkin interacting substrate; Parkin-interacting substrate; parkin-interacting sustrate; Zinc finger protein 746
基因别名: 2810407L07Rik; AI317225; PARIS; RGD1306209; Zfp746; ZNF746
UniProt ID: (Human) Q6NUN9, (Mouse) Q3U133
Entrez Gene ID: (Human) 155061, (Mouse) 69228, (Rat) 312303
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
ubiquitin protein ligase binding
transcription regulatory region DNA binding
metal ion binding
nucleic acid binding
DNA binding
C2H2 zinc finger transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of neuron death
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
