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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ESLKSRVQSY FDGIKADWLD SIRPQKEGDF RKEINKWWNN LSDGQR
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 93%.
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial intramembrane cleaving protease PARL; Presenilin-associated rhomboid-like protein, mitochondrial
基因别名: PARL; PRO2207; PSARL
Entrez Gene ID: (Human) 55486