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Invitrogen
PARP14 Polyclonal Antibody
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产品信息
PA5-82454
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AKEQESRADC ISEFIEWQYN DNNTSHCFNK MTNLKLEDAR REKKKTVDVK INHRHYTVNL NTYTATDTKG HSLSVQRLTK SKVDIPAHWS DMKQQNFCVV ELLPSDPEYN TVASKFNQTC S
Highest antigen sequence indentity to the following orthologs: Mouse - 56%, Rat - 53%.
靶标信息
Poly [ADP-ribose] polymerase 14 (PARP14) is a B aggressive lymphoma protein belonging to the PARP protein family. Poly ADP ribosylation is a DNA damage dependent post translational modification of histones and other nuclear proteins that mediates DNA repair. PARP proteins with a macrodomain are also involved in gene expression through transcriptional regulation. PARP14 controls STAT6 dependent transcription by enhancing binding to the promoter in the presence of a positive signal (i.e. IL4 stimulation).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosyltransferase diphtheria toxin-like 8; ARTD8; B aggressive lymphoma protein 2; B-aggressive lymphoma 2; collaborator of STAT6; PARP-14; Poly [ADP-ribose] polymerase 14; Protein mono-ADP-ribosyltransferase PARP14
基因别名: ARTD8; BAL2; KIAA1268; PARP-14; PARP14; pART8
UniProt ID: (Human) Q460N5
Entrez Gene ID: (Human) 54625
