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Invitrogen
PATJ Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-85444
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the N-terminus region of human PATJ. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (84%), Rat (85%), Bovine (88%).
Positive Control: RT-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: channel-interacting PDZ domain protein; channel-interacting PDZ domain-containing protein; inactivation no after-potential D-like protein; inactivation-no-afterpotential D-like; InaD-like 2; Inadl; PALS1-associated tight junction protein; PATJ; PDZ domain protein; PDZ domain protein; protein associated to tight junctions; unnamed protein product
基因别名: Cipp; hINADL; InaD-like; INADL; Inadl2; RGD1565362
UniProt ID: (Human) Q8NI35, (Rat) F1MAD2
Entrez Gene ID: (Human) 10207, (Rat) 140581
positive regulation of epithelial cell migration
microtubule organizing center organization
regulation of protein localization
establishment of apical/basal cell polarity
regulation of microtubule cytoskeleton organization
tight junction assembly
intracellular signal transduction
establishment or maintenance of epithelial cell apical/basal polarity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
