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Positive Samples: SKOV3, SW480, 293T, HeLa; Cellular Location: Apical cell membrane, Cell junction, Cell membrane, Cytoplasm, Peripheral membrane protein, perinuclear region, tight junction
Immunogen sequence: VRRKTSSSTS PLEPPSDRGT VVEPLKPPAL FLTGAVETET NVDGEDEEIK ERIDTLKNDN IQALEKLEKV PDSPENELKS RWENLLGPDY EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG GPVDTLGLLQ PEDELLEVNG MQLYGKSRRE AVSFLKEVPP PFTLVCCRRL FDDEASVDEP RRTETSLPET EVDHNMDVNT EEDDDGELAL W
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: channel-interacting PDZ domain protein; Channel-interacting PDZ domain-containing protein; inactivation no after-potential D-like protein; inactivation-no-afterpotential D-like; InaD-like protein; Inadl protein; novel ankyrin-repeat protein; PALS1-associated tight junction protein; PDZ domain protein; Protein associated to tight junctions
基因别名: Cipp; hINADL; InaD-like; INADL; Patj
UniProt ID: (Mouse) Q63ZW7
Entrez Gene ID: (Mouse) 12695, (Human) 10207