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MA5-15708 targets PAX8 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15708 immunogen is purified recombinant fragment of human PAX8 expressed in E. Coli.
MA5-15708 detects PAX8 which has a predicted molecular weight of approximately 60kDa.
This gene encodes a member of the paired box family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HGNC:8622; Paired box protein Pax-8; paired domain gene 8
基因别名: PAX8
UniProt ID: (Human) Q06710
Entrez Gene ID: (Human) 7849