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Invitrogen
PBXIP1 Polyclonal Antibody
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PBXIP1 Antibody (PA5-97157) in WB
Western blot analysis of PBXIP1 in extracts of various cell lines. Samples were incubated with PBXIP1 Polyclonal antibody (Product # PA5-97157) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-97157
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PBXIP1 (NP_0653852)
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MASCPDSDNS WVLAGSESLP VETLGPASRM DPESERALQA PHSPSKTDGK ELAGTMDGEG TLFQTESPQS GSILTEETEV KGTLEGDVCG VEPPGPGDTV VQGDLQETTV VTGLGPDTQD LEGQSPPQSL PSTPKAAWIR EEGRCSSSDD DTDVDMEGLR RRRGREAGPP QPMVPLAVEN QAGGEGAGGE; Positive Samples: HeLa, LO2, BT-474, A-549; Cellular Location: Cytoplasm, Nucleus, cytoskeleton
靶标信息
Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Hematopoietic PBX-interacting protein; pre-B-cell leukemia homeobox interacting protein 1; pre-B-cell leukemia transcription factor interacting protein 1; Pre-B-cell leukemia transcription factor-interacting protein 1
基因别名: 4732463H20Rik; HPIP; PBXIP1
UniProt ID: (Human) Q96AQ6, (Rat) A2VD12, (Mouse) Q3TVI8
Entrez Gene ID: (Human) 57326, (Rat) 310644, (Mouse) 229534
