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Bethyl Laboratories
PC4 Polyclonal Antibody
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PC4 Antibody (A301-162A) in IHC (P)
Detection of human and mouse PC4 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma (left) and mouse teratoma (right). Antibody: Affinity purified rabbit anti-PC4 (Product # A301-162A) (Lot 1) used at a dilution of 1:200 (1 µg/mL) and 1:1,000 (0.2 µg/mL). Detection: DAB.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A301-162A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 77 and 127 of human positive cofactor 4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.20 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Chicken and Orangutan
靶标信息
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activated RNA polymerase II transcription cofactor 4; p14; PC4; positive cofactor 4; RNA polymerase II transcriptional coactivator; single stranded DNA binding protein p9 precursor; single-stranded DNA-binding protein p9; SUB1 homolog, transcriptional regulator; TIS7; unnamed protein product
基因别名: p14; P15; P9; PC4; Rpo2tc1
UniProt ID: (Human) P53999, (Mouse) P11031
Entrez Gene ID: (Human) 10923, (Mouse) 20024
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