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Invitrogen
PCBP1 Polyclonal Antibody
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产品信息
PA5-116514
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human hnRNP E1/hnRNP E1/PCBP1 (NP_0061872)
偶联物
形式
Liquid
浓度
1.01 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: NIH/3T3, HepG2, MCF7, Mouse liver, Rat liver
Immunogen sequence: LRLVVPATQC GSLIGKGGCK IKEIRESTGA QVQVAGDMLP NSTERAITIA GVPQSVTECV KQICLVMLET LSQSPQGRVM TIPYQPMPAS SPVICAGGQD R
靶标信息
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-CP1; epididymis secretory protein Li 85; Heterogeneous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein E1; heterogenous nuclear ribonucleoprotein X; hnRNP E1; hnRNP-E1; Nucleic acid-binding protein SUB2.3; poly(rC) binding protein 1; Poly(rC)-binding protein 1
基因别名: [a]CP-1; alphaCP-1; HEL-S-85; hnRNP-E1; hnRNP-X; HNRPE1; HNRPX; PCBP1; RGD1561319; WBP17
UniProt ID: (Human) Q15365, (Mouse) P60335
Entrez Gene ID: (Human) 5093, (Rat) 500242, (Mouse) 23983
