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Invitrogen
PCK2 Recombinant Rabbit Monoclonal Antibody (E6C11)
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图: 1 / 11
PCK2 Antibody (MA572160) in IHC (P)
Immunohistochemistry analysis of PCK2 on paraffin-embedded Human Liver Cancer tissue. Antigen retrieval by boiling in sodium citrate buffer (pH 6.0) for 15 min. Samples were incubated with PCK2 Recombinant Monoclonal (Product # MA572160) using a dilution at 1:200 overnight at 4°C. Followed by DAB staining.
产品信息
MA572160
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
E6C11
抗原
Synthetic Peptide.
偶联物
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
纯化类型
Protein G
保存液
TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis secretory sperm binding protein; HGNC:8725; mtPCK2; PCK2; PEP carboxykinase; PEPCK-M; phosphoenolpyruvate carboxykinase 2 (mitochondrial) isoform PCK2_1; phosphoenolpyruvate carboxykinase 2 (mitochondrial) isoform PCK2_2; phosphoenolpyruvate carboxykinase 2 (mitochondrial) isoform PCK2_3; Phosphoenolpyruvate carboxykinase 2, mitochondrial; Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase; Serine/threonine-protein kinase PCK2; unnamed protein product
基因别名: 1810010O14Rik; 9130022B02Rik; mtPCK2; PCK2; PEPCK; PEPCK-M; PEPCK2
UniProt ID: (Human) Q16822, (Mouse) Q8BH04
Entrez Gene ID: (Human) 5106, (Mouse) 74551, (Rat) 361042
gluconeogenesis
oxaloacetate metabolic process
propionate catabolic process
positive regulation of insulin secretion
response to lipopolysaccharide
cellular response to insulin stimulus
response to starvation
glycerol biosynthetic process from pyruvate
hepatocyte differentiation
cellular response to glucose stimulus
cellular response to tumor necrosis factor
response to dexamethasone
cellular response to dexamethasone stimulus
pyruvate metabolic process
NADH oxidation
response to glucocorticoid
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