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Invitrogen
PCM1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102827
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PCM1(Accession Q15154), corresponding to amino acid residues N108-T158.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PCM1.
Target Information
PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mPCM-1; PCM-1; Pericentriolar material 1 protein; pericentriolar material gene 1
Gene Aliases: 2600002H09Rik; 9430077F19Rik; C030044G17Rik; PCM1
UniProt ID: (Mouse) Q9R0L6
Entrez Gene ID: (Mouse) 18536, (Rat) 81740
interkinetic nuclear migration
cell projection organization
cytoplasmic microtubule organization
microtubule anchoring
microtubule anchoring at centrosome
nonmotile primary cilium assembly
intraciliary transport involved in cilium morphogenesis
cilium assembly
negative regulation of neurogenesis
centrosome organization
protein localization to centrosome
positive regulation of intracellular protein transport
neuronal stem cell population maintenance
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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