Invitrogen

PCP4 Polyclonal Antibody

Name: PCP4 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-52209
Availability: InStock

高级验证

1个已发表图片

8 篇参考文献

查看其他6个PCP4抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

PCP4 Antibody in Immunohistochemistry (IHC)

图: 1 / 8

PCP4 Antibody (PA5-52209) in IHC

Immunofluorescence staining of PCP4 in mouse cerebral cortex using a PCP4 Polyclonal Antibody (Product # PA5-52209) shows strong positivity in the deep layers neurons.

PCP4 Antibody in Immunohistochemistry - Free Floating (IHC (Free))

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

PCP4 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PCP4 demonstrates antibody specificity. Immunohistochemical analysis of PCP4 using anti-PCP4 Polyclonal Antibody (Product # PA5-52209), shows significant staining of PCP4 in human cerebral cortex and shows minimal or weak staining in human liver tissues. The relative expression levels of PCP4 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image PCP4 Polyclonal Antibody

产品信息

PA5-52209

应用

建议稀释比

已发表文章

免疫组化 (IHC)

查看5篇已发表文章 5篇已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

免疫组化（冰冻） (IHC (F))

查看2篇已发表文章 2篇已发表文章

免疫组织化学（悬浮细胞） (IHC (Free))

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Fruit fly, Human, Mammal, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PCP4. Recombinant protein control fragment (Product #RP-88803).

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.10 mg/mL

10 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2645298

产品详细信息

Immunogen sequence: GAGATNGKDK TSGENDGQKK VQEEFDIDMD APETERAAVA IQSQFRKFQK KK

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

靶标信息

PCP-4 (Purkinje cell protein 4), also known as PCP4, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。