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Invitrogen
PCSK1 Polyclonal Antibody
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PCSK1 Antibody (PA5-29832) in IHC (P)
PCSK1 Polyclonal Antibody detects PC1/3 protein at cytosol and secreted on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. PCSK1 Polyclonal Antibody (Product # PA5-29832) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-29832
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human PC1/3. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.52 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HepG2, HCT116.
Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (93%), Pig (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.21.93; Furin homolog; NEC 1; Neuroendocrine convertase 1; PC1; PC3; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; Propeptide-processing protease; Proprotein convertase 1
基因别名: Att-1; BMIQ12; Nec-1; NEC1; PC1; PC3; PCSK1; Phpp-1; SPC3
UniProt ID: (Human) P29120, (Mouse) P63239
Entrez Gene ID: (Human) 5122, (Mouse) 18548
