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Invitrogen
PCSK6 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-32966
产品规格
种属反应
Bovine,
Horse,
Human,
Non-human primate,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 14 amino acid peptide from Cys-rich motif (CRM) region of human PACE4.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Rat, Bovine, Elephant, Horse, Rabbit (100%); Gibbon, Mouse, Dog, Panda, Pig (93%); Turkey, Chicken (86%).
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K.
靶标信息
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amino acid feature: RGD integrin-binding site, bp 1628 .. 1636; amino acid feature: cysteine-rich region, bp 2015 .. 2839; amino acid feature: potential N-linked glycosylation sites, bp 746 .. 748, bp 2672 .. 2674, or bp 2726 .. 2728; amino acid feature: p; kexin-like protease PC7A; paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Subtilisin - like endoprotease; subtilisin-like proprotein convertase 4; subtilisin/kexin-like protease PACE4
基因别名: PACE4; SPC4
UniProt ID: (Human) P29122, (Rat) Q63415
Entrez Gene ID: (Human) 5046, (Horse) 100057677, (Rabbit) 100347173, (Rat) 25507
proteolysis
glycoprotein metabolic process
protein processing
peptide hormone processing
regulation of BMP signaling pathway
nerve growth factor production
secretion by cell
plasma lipoprotein particle remodeling
zygotic determination of anterior/posterior axis, embryo
determination of left/right symmetry
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
