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Invitrogen
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Immunogen sequence: FCVHGNDITL TVDGRDTYEE VKQAGRYREC KRTQGVSTTD LVGRMLLVTK
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 100%
ECT (ethanolaminephosphate cytidyltransferase) is an important regulatory enzyme in the pathway for phosphatidylethanolamine (PE) biosynthesis. PE functions in cell signalling, membrane fusion, platelet activation, and cell cycle progression. Specialized forms of PE exist as plasmologens, natural cannabinoid anadimade, and glycosylated PE. The ECT enzyme acts in the second of three catalysis steps to produce CDP-ethanolamine from phosphoethanolamine (P-Etn). Study of ECT could help determine the role of plasmologens in disease, specifically lipid disorders such as peroxisomal diseases as well as neuronal degeneration associated with Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CTP:phosphoethanolamine cytidylyltransferase; Ethanolamine-phosphate cytidylyltransferase; Phosphorylethanolamine transferase
基因别名: 1110033E03Rik; ET; Pcyt2
UniProt ID: (Mouse) Q922E4
Entrez Gene ID: (Mouse) 68671