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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MQDPNADTEW NDILRKKGIL PPKESLKELE EEAEEEQRIL QQSVVKTYED MTLEELEDHE DEFNEEDERA IEMYRRRRLA EWKATKLKNK FGEVLEISGK DYVQEVTKAG EGLWVILHLY KQGIPLCALI NQHLSGLARK FPDVKFIKAI STTCIPNYPD RNLPTIFVYL EGDIKAQFIG PLVFGGMNLT RDELEWKLSE SGAIMTDLEE NPKKPIEDVL LSSVRRSVLM KRDSDSEGD
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling. PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding. Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HTPHLP; Phosducin-like protein 3; PhPL3; VIAF-1; Viral IAP-associated factor 1
基因别名: PDCL3; PhLP2A; VIAF1
Entrez Gene ID: (Human) 79031