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Fabgennix
PDE10A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PD10A-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide (Human) taken against a common sequence near the 250-325 amino acids downstream of N terminal region of PDE10A. Synthetic MAP.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase; FLJ11894; FLJ25677; PDE10A2 brain-specific isoform; testis-specific phosphodiesterase PDE10A2
Gene Aliases: PDE10A; Pde10a3
UniProt ID: (Mouse) Q8CA95, (Rat) Q9QYJ6
Entrez Gene ID: (Mouse) 23984, (Rat) 63885
nucleotide binding
catalytic activity
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
phosphoric diester hydrolase activity
drug binding
hydrolase activity
cAMP binding
cGMP binding
metal ion binding
3',5'-cyclic-GMP phosphodiesterase activity
phosphodiesterase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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