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Invitrogen
PDE1B Monoclonal Antibody (5C4A3)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-17147
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5C4A3
抗原
Purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-17147 targets PDE1B in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Rat samples.
The MA5-17147 immunogen is purified recombinant fragment of human PDE1B (amino acids: 370-536) expressed in E. Coli.
MA5-17147 detects PDE1B which has a predicted molecular weight of approximately 61.4kDa.
靶标信息
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 63 a Cam PDE; 63 a Cam-PDE; 63 kDa Cam-PDE; anti-oxidant protein 2; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Cam PDE 1B; Cam PDE1B; Cam-PDE 1B; cyclic nucleotide phosphodiesterase (CaM-PDE); Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; PDE 1B; PDES 1B; Phosphodiesterase; phosphodiesterase 1B, Ca2+calmodulin dependent; phosphodiesterase 1B1 Ca2+-calmodulin dependent 63 kDa; phosphodiesterase 1B1, Ca2+-calmodulin dependent, 63 kDa; phosphodiesterase IB calmodulin-dependent
基因别名: Aop2; PDE1B; Pde1b1; PDES1B
UniProt ID: (Rat) Q01066
Entrez Gene ID: (Rat) 29691
regulation of neurotransmitter levels
response to amphetamine
cAMP catabolic process
signal transduction
locomotory behavior
visual learning
monocyte differentiation
cellular response to macrophage colony-stimulating factor stimulus
regulation of dopamine metabolic process
serotonin metabolic process
cGMP catabolic process
cellular response to granulocyte macrophage colony-stimulating factor stimulus
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