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Fabgennix
PDE1C Polyclonal Antibody
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产品信息
PD1C-312AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; cyclic nucleotide phosphodiesterase 1 C; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Hcam3; phosphodiesterase 1C calmodulin-dependent (70kD)
基因别名: PDE1C; Pde1c2
UniProt ID: (Mouse) Q64338, (Rat) Q63421
Entrez Gene ID: (Mouse) 18575, (Rat) 81742
3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
calmodulin binding
phosphoric diester hydrolase activity
hydrolase activity
cAMP binding
metal ion binding
calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity
phosphodiesterase
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