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Abnova
PDGFA Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00005154-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PDGFA (NP_002598.4, 1 a.a. approximately 211 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MRTLACLLLL GCGYLAHVLA EEAEIPREVI ERLARSQIHS IRDLQRLLEI DSVGSEDSLD TSLRAHGVHA TKHVPEKRPL PIRRKRSIEE AVPAVCKTRT VIYEIPRSQV DPTSANFLIW PPCVEVKRCT GCCNTSSVKC QPSRVHHRSV KVAKVEYVRK KPKLKEVQVR LEEHLECACA TTSLNPDYRE EDTGRPRESG KKRKRKRLKP T
靶标信息
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PDGF A-chain; PDGF subunit A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; unnamed protein product
基因别名: PDGF-A; PDGF1
UniProt ID: (Human) P04085
Entrez Gene ID: (Human) 5154
angiogenesis
cell activation
hair follicle development
positive regulation of mesenchymal cell proliferation
cell-cell signaling
positive regulation of cell proliferation
response to wounding
organ morphogenesis
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
regulation of smooth muscle cell migration
cell projection assembly
actin cytoskeleton organization
positive regulation of cell migration
regulation of actin cytoskeleton organization
platelet-derived growth factor receptor-alpha signaling pathway
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
peptidyl-tyrosine autophosphorylation
wound healing
positive regulation of MAPK cascade
skin development
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
lung alveolus development
digestive tract development
negative chemotaxis
positive regulation of protein kinase B signaling
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
positive regulation of ERK1 and ERK2 cascade
regulation of glomerular mesangial cell proliferation
embryonic lung development
regulation of DNA biosynthetic process
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