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Agrisera
PDHE1-B/Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial Polyclonal Antibody
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PDHE1-B/Pyruvate dehydrogenase E1 component subunit beta-1, mitochondrial Antibody (AS23-4975) in WB
Samples: 1 - 40 µg of Arabidopsis thaliana Col-0 whole leaf extract. 2 - 40 µg of Arabidopsis thaliana mutant iar 4 (AT 1 G 24180), Arabidopsis thaliana pyruvate dehydrogenase E 1 a-like subunit. 3 - 40 µg of Arabidopsis thaliana mutant iar 4 l-1 (AT 1 G 59900), Arabidopsis thaliana pyruvate dehydrogenase E 1 a subunit. 4 - 40 µg of Arabidopsis thaliana mutant iar 4 l-2 (AT 1 G 59900), Arabidopsis thaliana ... View More
产品信息
AS23-4975
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated unique peptide derived from Arabidopsis thaliana PDHE1-B protein sequence.
偶联物
形式
Lyophilized
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
PDHE1 B, also called pyruvate dehydrogenase E1 beta subunit, is a core component of the mitochondrial pyruvate dehydrogenase complex in plants that converts pyruvate to acetyl CoA, linking glycolysis to the tricarboxylic acid cycle. The E1 enzyme is a heterotetramer composed of alpha and beta subunits; the beta subunit stabilizes the thiamine pyrophosphate dependent catalytic center and contributes to substrate binding and decarboxylation efficiency. PDHE1 B activity is regulated by reversible phosphorylation by pyruvate dehydrogenase kinases and dephosphorylation by phosphatases, as well as by metabolite effectors such as NADH and acetyl CoA that reflect energy status. Proper function supports respiration, biosynthesis of fatty acids and amino acids, and growth, while perturbation affects energy production, redox balance, and stress responses. Plant PDH shows tissue specific regulation, adjusting flux during developmental transitions and under environmental conditions such as drought and cold.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E1beta; PDHB; PDHBD; PDHE1-B; PDHE1B; PHE1B
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