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Invitrogen
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Immunogen sequence: SEQENNGDDAT ASSNPLAGQR KLTCSQDTLG SGDLPFSNES FISADCTDAD YLGIPVDECE RFR
Highest antigen sequence identity to the following orthologs - mouse 94%, rat 95%.
E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase PDZRN3; Ligand of Numb protein X 3; likely ortholog of mouse semaF cytoplasmic domain associated protein 3; PDZ domain-containing RING finger protein 3; Protein SEMACAP3; RING-type E3 ubiquitin transferase PDZRN3; Semaphorin cytoplasmic domain-associated protein 3
基因别名: KIAA1095; LNX3; PDZRN3; SEMACAP3; SEMCAP3
UniProt ID: (Human) Q9UPQ7
Entrez Gene ID: (Human) 23024