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NAT10 Monoclonal Antibody (3E3D8), PE

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NAT10 Monoclonal Antibody (3E3D8), PE

Product Details

PE-67465

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

0.40 µg/10^6 cells in a 100 µL suspension
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

3E3D8

Immunogen

NAT10 fusion protein Ag4355
3D Epitope / Immunogen

Conjugate

PE PE PE

Excitation/Emission Max

565/576 nm View spectra spectra

Form

Liquid

Concentration

0.2 mg/mL

Amount

20 µg

Purification

Protein A

Storage buffer

PBS with 0.5% BSA

Contains

0.09% sodium azide

Storage conditions

4°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: EAVSLLEEVI TPRKDLPPLL LKLNERPAER LDYLGVSYGL TPRLLKFWKR AGFVPVYLRQ TPNDLTGEHS CIMLKTLTDE DEADQGGWLA AFWKDFRRRF LALLSYQFST FSPSLALNII QNRNMGKPAQ PALSREELEA LFLPYDLKRL EMYSRNMVDY HLIMDMIPAI SRIYFLNQLG DLALSAAQSA LLLGIGLQHK SVDQLEKEIE LPSGQLMGLF NRIIRKVVKL FNEVQEKAIE EQMVAAKDVV MEPTMKTLSD DLDEAAKEFQ EKHKKEVGKL KSMDLSEYII RGDDEEWNEV LNKAGPNASI ISLKSDKKRK LEAKQEPKQS KKLKNRETKN KKDMKLKRKK

Target Information

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 18S rRNA cytosine acetyltransferase; hALP; N-acetyltransferase 10; N-acetyltransferase 10 (GCN5-related); N-acetyltransferase-like protein; novel putative ATPase domain containing protein; RNA cytidine acetyltransferase; unnamed protein product

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Gene Aliases: AI429152; ALP; KIAA1709; Kre33; NAT10; NET43; RGD1306717

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UniProt ID: (Human) Q9H0A0, (Mouse) Q8K224

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Entrez Gene ID: (Human) 55226, (Mouse) 98956, (Rat) 311257

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Function(s)
tRNA binding nucleotide binding RNA binding protein binding ATP binding N-acetyltransferase activity transferase activity transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups tRNA N-acetyltransferase activity DNA polymerase binding mRNA N-acetyltransferase activity rRNA cytidine N-acetyltransferase activity dihydrolipoamide branched chain acyltransferase activity sterol O-acyltransferase activity O-acyltransferase activity palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity carnitine O-acyltransferase activity acetyltransferase activity C-acyltransferase activity palmitoyltransferase activity N-acyltransferase activity acylglycerol O-acyltransferase activity serine O-acyltransferase activity O-acetyltransferase activity O-octanoyltransferase activity octanoyltransferase activity O-palmitoyltransferase activity S-acyltransferase activity S-acetyltransferase activity S-malonyltransferase activity malonyltransferase activity C-palmitoyltransferase activity succinyltransferase activity N-succinyltransferase activity O-succinyltransferase activity S-succinyltransferase activity sinapoyltransferase activity O-sinapoyltransferase activity peptidyl-lysine N6-myristoyltransferase activity peptidyl-lysine N6-palmitoyltransferase activity benzoyl acetate-CoA thiolase activity 3-hydroxybutyryl-CoA thiolase activity 3-ketopimelyl-CoA thiolase activity N-palmitoyltransferase activity myristoyltransferase activity acyl-CoA N-acyltransferase activity protein-cysteine S-myristoyltransferase activity protein-cysteine S-acyltransferase activity dihydrolipoamide S-acyltransferase activity glucosaminyl-phosphotidylinositol O-acyltransferase activity ergosterol O-acyltransferase activity lanosterol O-acyltransferase activity naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity 2-methylhexanoyl-CoA C-acetyltransferase activity butyryl-CoA 2-C-propionyltransferase activity 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity L-2-aminoadipate N-acetyltransferase activity UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity keto acid formate lyase activity Ras palmitoyltransferase activity poly(A) RNA binding azetidine-2-carboxylic acid acetyltransferase activity peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor acetyl-CoA:L-lysine N6-acetyltransferase RNA processing factor
Process(es)
rRNA modification tRNA wobble cytosine modification rRNA processing regulation of translation protein acetylation tRNA processing RNA modification regulation of centrosome duplication rRNA metabolic process negative regulation of telomere maintenance via telomerase ribosome biogenesis ribosomal small subunit biogenesis positive regulation of translation tRNA acetylation rRNA acetylation involved in maturation of SSU-rRNA biological_process metabolic process
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