Invitrogen

PEX13 Polyclonal Antibody

Name: PEX13 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-56941

高级验证

查看其他5个PEX13抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (8)
高级验证 (1)

PEX13 Antibody in Immunocytochemistry (ICC/IF)

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PEX13 Antibody (PA5-56941) in ICC/IF

Immunofluorecent analysis of PEX13 in human cell line U-2 OS using PEX13 Polyclonal Antibody (Product # PA5-56941). Staining shows localization to vesicles.

PEX13 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

PEX13 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of PEX13 demonstrates antibody specificity. Immunohistochemical analysis of PEX13 using anti-PEX13 Polyclonal Antibody (Product # PA5-56941), shows significant staining of PEX13 in human testis and shows minimal or weak staining in human pancreas tissues. The relative expression levels of PEX13 within each tissue is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image PEX13 Polyclonal Antibody

产品信息

PA5-56941

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PEX13. Recombinant protein control fragment (Product #RP-102617).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2645404

产品详细信息

Immunogen sequence: GLIPANYVKI LGKRKGRKTV ESSKVSKQQQ SFTNPTLTKG ATVADSLDEQ EAAFESVFVE TNKVPVAPDS IGKDG

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

靶标信息

PEX13 (Peroxisomal Biogenesis Factor 13) is a gene located on chromosome 2p15 that encodes a peroxisomal membrane protein essential for the biogenesis and function of peroxisomes, which are cellular organelles involved in lipid metabolism and detoxification of reactive oxygen species. PEX13 is a component of the peroxisomal import machinery that specifically recognizes and binds to peroxisomal targeting signal 1 (PTS1) containing proteins, facilitating their import into the peroxisome matrix. Mutations in the PEX13 gene can lead to Zellweger spectrum disorders, a group of peroxisome biogenesis disorders (PBDs) characterized by defects in multiple peroxisomal metabolic pathways, leading to severe developmental issues, neurological deficits, and often early lethality. Studies of PEX13 have helped elucidate the mechanisms of peroxisomal protein import and the broader implications of peroxisomal dysfunction in human disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。