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Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Rhesus Monkey (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8. PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome, neonatal adrenoleukodystrophy, infantile Refsum disease, and classical rhizomelic chondrodysplasia punctata. Alternatively spliced transcript variants have been identified for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20695; Peroxin-26; Peroxisome assembly protein 26; peroxisome biogenesis disorder, complementation group 8; peroxisome biogenesis disorder, complementation group A; peroxisome biogenesis factor 26
基因别名: PBD7A; PBD7B; PEX26; PEX26M1T; Pex26pM1T
UniProt ID: (Human) Q7Z412
Entrez Gene ID: (Human) 55670