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Invitrogen
PF4V1 Polyclonal Antibody
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产品信息
PA5150247
产品规格
种属反应
Human
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant Platelet Factor 4 Variant 1 (PF4V1) (Met1-Ser104)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The PF4V1 (Platelet Factor 4 Variant 1) gene, located on chromosome 4q12, encodes a protein that is a member of the CXC chemokine family, sharing significant homology with platelet factor 4 (PF4/CXCL4). PF4V1 is primarily expressed in megakaryocytes and platelets, playing a role in modulating coagulation and inflammatory responses. The protein has chemotactic activity, attracting immune cells to sites of injury or inflammation. Furthermore, PF4V1 can bind to heparin, influencing the anticoagulant activity of heparin and potentially impacting hemostasis and thrombosis. Research suggests that variations in the expression or function of PF4V1 might contribute to different pathological conditions, including cardiovascular disease and inflammatory disorders.
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生物信息学
蛋白别名: C-X-C motif chemokine 4; C-X-C motif chemokine 4 variant; CXCL4L1; PF4alt; PF4var1; Platelet factor 4 variant; platelet factor 4, variant 1 (PF4-like)
基因别名: CXCL4L1; CXCL4V1; PF4-ALT; PF4A; PF4V1; SCYB4V1
UniProt ID: (Human) P10720
Entrez Gene ID: (Human) 5197
